BDBM50307158 5-(3-(2,5-dichlorophenyl)propyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::CHEMBL597383

SMILES Nc1nc(N)c2c(CCCc3cc(Cl)ccc3Cl)c[nH]c2n1

InChI Key InChIKey=KPMDOQJJXIXPQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307158   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50307158(5-(3-(2,5-dichlorophenyl)propyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50307158(5-(3-(2,5-dichlorophenyl)propyl)-7H-pyrrolo[2,3-d]...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed