BDBM50307160 5-((methyl(5,6,7,8-tetrahydronaphthalen-1-yl)amino)methyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine::CHEMBL589525

SMILES CN(Cc1c[nH]c2nc(N)nc(N)c12)c1cccc2CCCCc12

InChI Key InChIKey=AVBLUIHURQRIDH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307160   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50307160(5-((methyl(5,6,7,8-tetrahydronaphthalen-1-yl)amino...)
Affinity DataIC50: 870nMAssay Description:Inhibition of Toxoplasma gondii DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50307160(5-((methyl(5,6,7,8-tetrahydronaphthalen-1-yl)amino...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of rat liver DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed