BDBM50307169 2,4-Diamino-5-methyl-6-(3',4',5'-trimethoxyphenylthio)pyrrolo[2,3-d]pyrimidine::CHEMBL597771

SMILES COc1cc(Sc2[nH]c3nc(N)nc(N)c3c2C)cc(OC)c1OC

InChI Key InChIKey=QASSHRWUUXMZLT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307169   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50307169(2,4-Diamino-5-methyl-6-(3',4',5'-trimethoxyphenylt...)
Affinity DataIC50: 686nMAssay Description:Inhibition of Toxoplasma gondii DHFR using dihydrofolic acid substrate and NADPH cofactor by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50307169(2,4-Diamino-5-methyl-6-(3',4',5'-trimethoxyphenylt...)
Affinity DataIC50: 2.46E+4nMAssay Description:Inhibition of rat liver DHFR using dihydrofolic acid substrate and NADPH cofactor by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed