BDBM50307428 3-[2-({[1-(3-Fluoro-4-methoxyphenyl)-3-methylbutyl]-amino}carbonyl)-4-(phenoxymethyl)phenyl]propanoic acid::CHEMBL606195

SMILES COc1ccc(cc1F)C(CC(C)C)NC(=O)c1cc(COc2ccccc2)ccc1CCC(O)=O

InChI Key InChIKey=WWXJECJLRYIVOD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307428   

TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50307428(3-[2-({[1-(3-Fluoro-4-methoxyphenyl)-3-methylbutyl...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50307428(3-[2-({[1-(3-Fluoro-4-methoxyphenyl)-3-methylbutyl...)
Affinity DataIC50:  42nMAssay Description:Antagonist activity at mouse EP3 receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase intracellular calcium level in prese...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed