BDBM50307486 5,5-difluoro-1,3,7,9-tetramethyl-10-(4-(1-((S)-1-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-ylamino)-1-oxo-3-(perfluorophenyl)propan-2-ylamino)-1-oxo-3-phenylpropan-2-ylamino)-1-oxo-3-phenylpropan-2-yl)-1H-1,2,3-triazol-4-yl)butyl)-5H-dipyrrolo[1,2-c:1',2'-f][1,3,2]diazaborinin-4-ium-5-uide::CHEMBL578518

SMILES CC1=CC(C)=[N+]2C1=C(CCCCc1cn([C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc3c(F)c(F)c(F)c(F)c3F)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]3(C)CO3)nn1)c1c(C)cc(C)n1[B-]2(F)F

InChI Key InChIKey=FERPMTXJZUHNMW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50307486   

TargetProteasome subunit beta type-5(Human)
Gorlaeus Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307486BDBM50307486(5,5-difluoro-1,3,7,9-tetramethyl-10-(4-(1-((S)-1-(...)
Affinity DataIC50: 300nMAssay Description:Inhibition of 26S proteasome beta 5 using LLVY as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Gorlaeus Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307486BDBM50307486(5,5-difluoro-1,3,7,9-tetramethyl-10-(4-(1-((S)-1-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 26S proteasome beta 1 using nLPnLD as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Gorlaeus Laboratories

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50307486BDBM50307486(5,5-difluoro-1,3,7,9-tetramethyl-10-(4-(1-((S)-1-(...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 26S proteasome beta 2 using RLR as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed