BDBM50307536 8-[(1-Acetylpiperidin-4-yl)amino]-N,1-dimethyl-4,5-dihydro-1Hpyrazolo[4,3-h]quinazoline-3-carboxamide::CHEMBL599427

SMILES CNC(=O)c1nn(C)c-2c1CCc1cnc(NC3CCN(CC3)C(C)=O)nc-21

InChI Key InChIKey=AOJLBKYLAVRMQT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50307536   

TargetAurora kinase A(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50307536(8-[(1-Acetylpiperidin-4-yl)amino]-N,1-dimethyl-4,5...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50307536(8-[(1-Acetylpiperidin-4-yl)amino]-N,1-dimethyl-4,5...)
Affinity DataIC50:  32nMAssay Description:Inhibition of CDK2/Cyclin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed