BDBM50307886 5'-((1H-1,2,4-triazol-1-yl)methyl)-2'-cyanobiphenyl-4-yl sulfamate::CHEMBL598199

SMILES NS(=O)(=O)Oc1ccc(cc1)-c1cc(Cn2cncn2)ccc1C#N

InChI Key InChIKey=GSLZUVHJGUWMRX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50307886   

TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50307886(5'-((1H-1,2,4-triazol-1-yl)methyl)-2'-cyanobipheny...)
Affinity DataIC50:  2nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50307886(5'-((1H-1,2,4-triazol-1-yl)methyl)-2'-cyanobipheny...)
Affinity DataIC50:  35nMAssay Description:Inhibition of steroid sulfatase in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50307886(5'-((1H-1,2,4-triazol-1-yl)methyl)-2'-cyanobipheny...)
Affinity DataIC50:  2nMAssay Description:Inhibition of aromatse in human JEG3 cells by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50307886(5'-((1H-1,2,4-triazol-1-yl)methyl)-2'-cyanobipheny...)
Affinity DataIC50:  35nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed