BDBM50308183 1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]azetidin-3-amine::CHEMBL598443

SMILES NC1CN(c2ccc3[nH]nc(S(=O)(=O)c4cccc5ccccc45)c3c2)C1

InChI Key InChIKey=PEENLCMAOCPFKF-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50308183   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308183BDBM50308183(1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]azetidin...)
Affinity DataKi:  3.55nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308183BDBM50308183(1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]azetidin...)
Affinity DataIC50: 16.5nMAssay Description:Antagonist activity at human cloned 5HT6 receptor expressed in human HeLa cells assessed as intracellular cAMP formation by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308183BDBM50308183(1-[3-(1-Naphthylsulfonyl)-1H-indazol-5-yl]azetidin...)
Affinity DataKi:  97.9nMAssay Description:Displacement of [3H]5HT from human 5HT2B receptor expressed in CHO cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed