BDBM50308267 2-{4-[(Benzylmethylamino)methyl]benzylidene}-6-(4-piperidin-1-yl-butoxy)indan-1-one::CHEMBL597822

SMILES CN(Cc1ccccc1)Cc1ccc(\C=C2/Cc3ccc(OCCCCN4CCCCC4)cc3C2=O)cc1

InChI Key InChIKey=ZZRZJQCUHYDGJB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308267   

TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50308267(2-{4-[(Benzylmethylamino)methyl]benzylidene}-6-(4-...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50308267(2-{4-[(Benzylmethylamino)methyl]benzylidene}-6-(4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BuChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed