BDBM50308269 2-{4-[(Benzylmethylamino)methyl]benzylidene}-6-(4-diethylaminobutoxy)indan-1-one::CHEMBL598645

SMILES CCN(CC)CCCCOc1ccc2C\C(=C/c3ccc(CN(C)Cc4ccccc4)cc3)C(=O)c2c1

InChI Key InChIKey=RZMDKGRCDDUXCM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308269   

TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50308269(2-{4-[(Benzylmethylamino)methyl]benzylidene}-6-(4-...)
Affinity DataIC50: 890nMAssay Description:Inhibition of human recombinant AChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50308269(2-{4-[(Benzylmethylamino)methyl]benzylidene}-6-(4-...)
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of human BuChE preincubated for 20 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed