BDBM50308605 2-(2-(5-Bromo-2-hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one::CHEMBL592457

SMILES Oc1csc(N=NCc2cc(Br)ccc2O)n1

InChI Key InChIKey=RVNYRYCNOIAMAM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308605   

TargetEpidermal growth factor receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50308605(2-(2-(5-Bromo-2-hydroxybenzylidene)hydrazinyl)thia...)
Affinity DataIC50: 90nMAssay Description:Inhibition of cloned EGFR autophosphorylation expressed in baculovirus-infected Sf9 cells by solid-phase ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50308605(2-(2-(5-Bromo-2-hydroxybenzylidene)hydrazinyl)thia...)
Affinity DataIC50: 420nMAssay Description:Inhibition of human cloned HER2 autophosphorylation expressed in baculovirus-infected Sf9 cells by solid-phase ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed