BDBM50308866 3-Chloro-N-[3-(4-dimethylaminomethyl-phenylcarbamoyl)-benzyl]-4-methoxy-benzamide::CHEMBL592709

SMILES COc1ccc(cc1Cl)C(=O)NCc1cccc(c1)C(=O)Nc1ccc(CN(C)C)cc1

InChI Key InChIKey=VYLVEERKOLDJOU-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50308866   

TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308866(3-Chloro-N-[3-(4-dimethylaminomethyl-phenylcarbamo...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308866(3-Chloro-N-[3-(4-dimethylaminomethyl-phenylcarbamo...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human ROCK2 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308866(3-Chloro-N-[3-(4-dimethylaminomethyl-phenylcarbamo...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of PKCepsilonMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase N2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308866(3-Chloro-N-[3-(4-dimethylaminomethyl-phenylcarbamo...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of PKN2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308866(3-Chloro-N-[3-(4-dimethylaminomethyl-phenylcarbamo...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human CYP3A4 by LCMS/MS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308866(3-Chloro-N-[3-(4-dimethylaminomethyl-phenylcarbamo...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human CYP1A2 by LCMS/MS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308866(3-Chloro-N-[3-(4-dimethylaminomethyl-phenylcarbamo...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human CYP2C9 by LCMS/MS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308866(3-Chloro-N-[3-(4-dimethylaminomethyl-phenylcarbamo...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human CYP2D6 by LCMS/MS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCell division control protein 42 homolog(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50308866(3-Chloro-N-[3-(4-dimethylaminomethyl-phenylcarbamo...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed