BDBM50309024 CHEMBL604999::N-(3-((5'-chloro-3,3'-difluoro-2'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl)methylamino)-1H-pyrazol-4-yl)-3-methoxyisoxazole-5-carboxamide

SMILES COc1cc(C(=O)Nc2cn[nH]c2NCc2ccc(-c3cc(Cl)cc(F)c3-c3noc(C)n3)cc2F)on1

InChI Key InChIKey=CKDCETIXLNSACD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50309024   

TargetB1 bradykinin receptor(Human)
Jerini

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50309024BDBM50309024(N-(3-((5'-chloro-3,3'-difluoro-2'-(5-methyl-1,2,4-...)
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at bradykinin B1 receptor in human IMR90 cells pretreated with IL1-beta assessed as inhibition of DAKD-induced calcium mobilizati...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed