BDBM50309188 4-(2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)-2-methoxyphenol::CHEMBL590793::US10688093, Compound 382_0314_0087::US11701353, Compound 382_0314_0087

SMILES COc1cc(ccc1O)-c1cc(cnc1N)-c1cc(OC)c(OC)c(OC)c1

InChI Key InChIKey=GUBPYJJIGUBALI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50309188   

TargetTyrosine-protein kinase Fyn(Human)
Pathways Neuro Pharma

US Patent
LigandPNGBDBM50309188(4-(2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)...)
Affinity DataIC50: 80.6nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetTyrosine-protein kinase Fyn(Human)
Pathways Neuro Pharma

US Patent
LigandPNGBDBM50309188(4-(2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)...)
Affinity DataIC50: 116nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309188(4-(2-amino-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl)...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed