BDBM50309190 2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)-N-[2-(DIMETHYLAMINO)ETHYL]PYRIDINE-3-CARBOXAMIDE::2-Amino-5-(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)-N-(2-(dimethylamino)ethyl)nicotinamide::CHEMBL598973

SMILES CN(C)CCNC(=O)c1cc(cnc1N)-c1scc2OCCOc12

InChI Key InChIKey=XGNFTBBPLXKQQH-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309190   

TargetSerine/threonine-protein kinase Chk2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309190(2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-Y...)
Affinity DataIC50:  700nMAssay Description:Inhibition of CHK2 in human HT29 cellsMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Chk1(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50309190(2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-Y...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of CHK1 by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed