BDBM50309388 4-(3-(4-acetyl-1,4-diazepane-1-carbonyl)-4-fluorobenzyl)-6,7-dichloropyrrolo[1,2-a]pyrazin-1(2H)-one::CHEMBL596721

SMILES CC(=O)N1CCCN(CC1)C(=O)c1cc(Cc2c[nH]c(=O)c3cc(Cl)c(Cl)n23)ccc1F

InChI Key InChIKey=DYJWTCOVYPYXKL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50309388   

TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50309388(4-(3-(4-acetyl-1,4-diazepane-1-carbonyl)-4-fluorob...)
Affinity DataIC50: 19nMAssay Description:Inhibition of PARP1 by topcount microplate scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed