BDBM50309602 (+)-3-(2-(2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)ethyl)-1H-indole-5-carbonitrile::(-)-3-(2-(2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)ethyl)-1H-indole-5-carbonitrile::3-(2-(2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)ethyl)-1H-indole-5-carbonitrile::CHEMBL609908

SMILES CN1CCc2ccccc2C1CCc1c[nH]c2ccc(cc12)C#N

InChI Key InChIKey=PQVFTFGHDAAJKQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50309602   

TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309602((+)-3-(2-(2-methyl-1,2,3,4-tetrahydroisoquinolin-1...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [I125]RTI-55 from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309602((+)-3-(2-(2-methyl-1,2,3,4-tetrahydroisoquinolin-1...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [I125]RTI-55 from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309602((+)-3-(2-(2-methyl-1,2,3,4-tetrahydroisoquinolin-1...)
Affinity DataIC50: 4.20nMAssay Description:Displacement of [I125]RTI-55 from human SERT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309602((+)-3-(2-(2-methyl-1,2,3,4-tetrahydroisoquinolin-1...)
Affinity DataIC50: 620nMAssay Description:Displacement of [I125]RTI-55 from human DAT transfected in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50309602((+)-3-(2-(2-methyl-1,2,3,4-tetrahydroisoquinolin-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]nisoxetine from human NET transfected in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed