BDBM50309829 1-((3-(2-phenylpropylthio)phenylimino)methyl)naphthalen-2-ol::CHEMBL596656

SMILES CC(CSc1cccc(c1)\N=C\c1c(O)ccc2ccccc12)c1ccccc1

InChI Key InChIKey=WEGBYIMIALFDLG-WPWMEQJKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50309829   

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309829(1-((3-(2-phenylpropylthio)phenylimino)methyl)napht...)
Affinity DataIC50:  4.03E+4nMAssay Description:Inhibition of human recombinant SIRT1 by Flour de Lys assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Institute of Psychiatry and Neuroscience of Paris

Curated by ChEMBL
LigandPNGBDBM50309829(1-((3-(2-phenylpropylthio)phenylimino)methyl)napht...)
Affinity DataIC50:  4.03E+4nMAssay Description:Inhibition of human N-terminal GST-tagged SIRT1 expressed in Escherichia coli using Arg-His- Lys-Lys(Ac) as substrate after 1 hr by Fluor de Lys fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50309829(1-((3-(2-phenylpropylthio)phenylimino)methyl)napht...)
Affinity DataIC50:  1.92E+4nMAssay Description:Inhibition of human SIRT2 expressed in Escherichia coli using Gln-Pro-Lys-Lys(Ac) as substrate after 1 hr by Fluor de Lys fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50309829(1-((3-(2-phenylpropylthio)phenylimino)methyl)napht...)
Affinity DataIC50:  1.92E+4nMAssay Description:Inhibition of human recombinant SIRT2 by Flour de Lys assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed