BDBM50310796 CHEMBL1080975::N-((3'-chlorobiphenyl-4-yl)methyl)-3-methyl-3-phenylpiperidine-1-carboxamide

SMILES CC1(CCCN(C1)C(=O)NCc1ccc(cc1)-c1cccc(Cl)c1)c1ccccc1

InChI Key InChIKey=SFAHBRRRIPXYTB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50310796   

TargetBifunctional epoxide hydrolase 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310796(CHEMBL1080975 | N-((3'-chlorobiphenyl-4-yl)methyl)...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBifunctional epoxide hydrolase 2(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310796(CHEMBL1080975 | N-((3'-chlorobiphenyl-4-yl)methyl)...)
Affinity DataIC50:  7nMAssay Description:Inhibition of rat soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310796(CHEMBL1080975 | N-((3'-chlorobiphenyl-4-yl)methyl)...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Nav1.5 channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCytochrome P450 2D6(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310796(CHEMBL1080975 | N-((3'-chlorobiphenyl-4-yl)methyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEpoxide hydrolase 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50310796(CHEMBL1080975 | N-((3'-chlorobiphenyl-4-yl)methyl)...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of human microsomal epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed