BDBM50310921 CHEMBL1080068::{6-Chloro-2-[(pyridin-3-ylmethyl)-amino]-thieno[3,2-d]pyrimidin-4-yl}-thiophen-2-yl-methanone

SMILES Clc1cc2nc(NCc3cccnc3)nc(C(=O)c3cccs3)c2s1

InChI Key InChIKey=HWFLOIWTEDBAFA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50310921   

TargetAdenosine receptor A2a(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50310921(CHEMBL1080068 | {6-Chloro-2-[(pyridin-3-ylmethyl)-...)
Affinity DataIC50:  62nMAssay Description:Antagonist activity at human adeosine A2A receptor expressed in CHOK1 cells assessed as inhibition of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAdenosine receptor A2b(Human)
Vernalis (R&D)

Curated by ChEMBL
LigandPNGBDBM50310921(CHEMBL1080068 | {6-Chloro-2-[(pyridin-3-ylmethyl)-...)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at human adeosine A2B receptor expressed in CHOK1 cells assessed as inhibition of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed