BDBM50311528 (S,E)-N-(4-chlorobenzyl)-2-(5,13-dioxo-1-oxa-4-azacyclotridec-8-en-6-yl)acetamide::CHEMBL1076352

SMILES O=C(C[C@@H]1C/C=C/CCCC(=O)OCCNC1=O)NCc1ccc(Cl)cc1

InChI Key InChIKey=XOSBLLGXOWRWPW-UHFFFAOYSA-N

Data  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311528   

TargetSonic hedgehog protein(Human)
Massachusetts General Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311528BDBM50311528((S,E)-N-(4-chlorobenzyl)-2-(5,13-dioxo-1-oxa-4-aza...)
Affinity DataKd: >5.00E+4nMAssay Description:Binding affinity to recombinant Shh N-terminal peptide by surface plasma resonanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Massachusetts General Hospital

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50311528BDBM50311528((S,E)-N-(4-chlorobenzyl)-2-(5,13-dioxo-1-oxa-4-aza...)
Affinity DataEC50:  7.00E+4nMAssay Description:Inhibition of SHH in mouse Shh Light2 cells after 30 hrs by GLI-responsive bright glo luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed