BDBM50311555 2-(1-(6-(2-ethylphenoxy)pyrimidin-4-yl)piperidin-4-yloxy)-5-fluoropyrimidin-4-amine::CHEMBL1079735

SMILES CCc1ccccc1Oc1cc(ncn1)N1CCC(CC1)Oc1ncc(F)c(N)n1

InChI Key InChIKey=QFUNVSAPMCROCD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311555   

TargetDeoxycytidine kinase(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311555(2-(1-(6-(2-ethylphenoxy)pyrimidin-4-yl)piperidin-4...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human dCKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetDeoxycytidine kinase(Human)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50311555(2-(1-(6-(2-ethylphenoxy)pyrimidin-4-yl)piperidin-4...)
Affinity DataEC50:  61nMAssay Description:Inhibition of dCK in human CCRF-CEM assessed as inhibition of Ara-C phosohorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed