BDBM50311976 (R)-2-(4-phenyl-1-((tetrahydrofuran-2-yl)methyl)-1H-imidazol-5-yl)thiazolo[5,4-d]pyrimidin-7-amine::CHEMBL1079772

SMILES Nc1ncnc2sc(nc12)-c1c(ncn1C[C@H]1CCCO1)-c1ccccc1

InChI Key InChIKey=XFQVAGHLSGFVLY-CYBMUJFWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50311976   

TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50311976((R)-2-(4-phenyl-1-((tetrahydrofuran-2-yl)methyl)-1...)
Affinity DataIC50:  370nMAssay Description:Inhibition of Tie-2 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed