BDBM50312096 CHEMBL1080481::N-(3-(3-chlorobenzamido)phenyl)-2-methoxybenzamide

SMILES COc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccc(Cl)c2)c1

InChI Key InChIKey=LRXRNLQJXRYLBZ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312096   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50312096(CHEMBL1080481 | N-(3-(3-chlorobenzamido)phenyl)-2-...)
Affinity DataKi:  301nMAssay Description:Displacement of [3H]3-methoxy-5-(2-pyridinylethynyl) pyridine from mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50312096(CHEMBL1080481 | N-(3-(3-chlorobenzamido)phenyl)-2-...)
Affinity DataIC50:  880nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK293A cells assessed as inhibition of glutamate-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50312096(CHEMBL1080481 | N-(3-(3-chlorobenzamido)phenyl)-2-...)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at mGluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed