BDBM50312653 1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethyl-6-chloro-3-[2,2-difluoro-2-phenylethylamino]pyrazinone::CHEMBL1088332

SMILES [#7]\[#6](-[#7])=[#7]\[#8]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-n1c(Cl)cnc(-[#7]-[#6]C(F)(F)c2ccccc2)c1=O

InChI Key InChIKey=VZFNTNJRDFGPHL-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50312653   

TargetProthrombin(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312653(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312653(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of urokinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312653(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312653(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312653(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor VII(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312653(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil elastase(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50312653(1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethy...)
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed