BDBM50312653 1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethyl-6-chloro-3-[2,2-difluoro-2-phenylethylamino]pyrazinone::CHEMBL1088332
SMILES [#7]\[#6](-[#7])=[#7]\[#8]-[#6]-[#6]-[#7]-[#6](=O)-[#6]-n1c(Cl)cnc(-[#7]-[#6]C(F)(F)c2ccccc2)c1=O
InChI Key InChIKey=VZFNTNJRDFGPHL-UHFFFAOYSA-N
Data 7 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50312653
Affinity DataKi: 1.70nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of urokinaseMore data for this Ligand-Target Pair
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of cathepsin GMore data for this Ligand-Target Pair
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of chymaseMore data for this Ligand-Target Pair
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
TargetCoagulation factor VII(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
TargetNeutrophil elastase(Human)
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataKi: >2.60E+4nMAssay Description:Inhibition of human leukocyte elastaseMore data for this Ligand-Target Pair