BDBM50312736 (S)-(4-(5-amino-6-(2,6-dichlorobenzyloxy)pyrazin-2-yl)phenyl)(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl)methanone::CHEMBL1088599

SMILES Nc1ncc(nc1OCc1c(Cl)cccc1Cl)-c1ccc(cc1)C(=O)N1CCC[C@H]1CN1CCCC1

InChI Key InChIKey=DUKXMVRXTBCVNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312736   

LigandPNGBDBM50312736((S)-(4-(5-amino-6-(2,6-dichlorobenzyloxy)pyrazin-2...)
Affinity DataIC50: 57nMAssay Description:Inhibition of human CSF1R autophosphorylation expressed in HEK293 cells after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed