BDBM50312958 CHEMBL1082028::N-(2-(2-fluorophenyl)-3,4'-bipyridin-6-yl)cyclopropanecarboxamide

SMILES Fc1ccccc1-c1nc(NC(=O)C2CC2)ccc1-c1ccncc1

InChI Key InChIKey=QUVRBMYDRIIHLI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50312958   

TargetAdenosine receptor A2b(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50312958(N-(2-(2-fluorophenyl)-3,4'-bipyridin-6-yl)cyclopro...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cells after 60 mins by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50312958(N-(2-(2-fluorophenyl)-3,4'-bipyridin-6-yl)cyclopro...)
Affinity DataKi:  61nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in human HeLa cells after 1 hr by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50312958(N-(2-(2-fluorophenyl)-3,4'-bipyridin-6-yl)cyclopro...)
Affinity DataKi:  123nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cells after 90 mins by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50312958(N-(2-(2-fluorophenyl)-3,4'-bipyridin-6-yl)cyclopro...)
Affinity DataKi:  817nMAssay Description:Displacement of [3H]NECA from human adenosine A3 receptor expressed in human HeLa cells after 3 hrs by filtration binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed