BDBM50313106 CHEMBL1081991::N-cyclopropyl-3-(1-(2,6-difluorophenyl)-1H-pyrazolo[4,3-d]pyridazin-4-ylamino)-4-methylbenzamide

SMILES Cc1ccc(C(=O)NC2CC2)cc1Nc1nncc2c1cnn2-c1c(F)cccc1F

InChI Key InChIKey=FBBSXSUJJZYEKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313106   

TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50313106BDBM50313106(N-cyclopropyl-3-(1-(2,6-difluorophenyl)-1H-pyrazol...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human recombinant p38alpha assessed as phosphorylated ATF2 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed