BDBM50313124 1-(1-methylpyrrolidin-3-yl)-3-(naphthalen-1-ylsulfonyl)-1H-indole::CHEMBL1080381

SMILES CN1CCC(C1)n1cc(c2ccccc12)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=FXHPFKQLFZFAMD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313124   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313124(1-(1-methylpyrrolidin-3-yl)-3-(naphthalen-1-ylsulf...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313124(1-(1-methylpyrrolidin-3-yl)-3-(naphthalen-1-ylsulf...)
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced intracellular cAMP level after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed