BDBM50313147 3-(3-chlorophenylsulfonyl)-1-(pyrrolidin-3-yl)-1H-indole::CHEMBL1094370

SMILES Clc1cccc(c1)S(=O)(=O)c1cn(C2CCNC2)c2ccccc12

InChI Key InChIKey=IYJZDLOAWKCXJN-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313147   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313147(3-(3-chlorophenylsulfonyl)-1-(pyrrolidin-3-yl)-1H-...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50313147(3-(3-chlorophenylsulfonyl)-1-(pyrrolidin-3-yl)-1H-...)
Affinity DataEC50:  125nMAssay Description:Agonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as effect on 5HT-induced intracellular cAMP level after 10 mins by ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed