BDBM50313159 (S)-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N4-(5-methylthiazol-2-yl)-6-morpholinopyrimidine-2,4-diamine::CHEMBL1088030

SMILES C[C@H](Nc1nc(Nc2ncc(C)s2)cc(n1)N1CCOCC1)c1ncc(F)cn1

InChI Key InChIKey=ODONICFHLYWURU-LBPRGKRZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50313159   

TargetTyrosine-protein kinase JAK2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50313159((S)-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N4-(5-met...)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant JAK2 kinase in presence of 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50313159((S)-N2-(1-(5-fluoropyrimidin-2-yl)ethyl)-N4-(5-met...)
Affinity DataIC50: >3.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed