BDBM50313854 (R)-5-chloro-1-(1-cyclopropylethyl)-3-(6-methoxy-2-methylpyridin-3-ylamino)pyrazin-2(1H)-one::CHEMBL1084413

SMILES COc1ccc(Nc2nc(Cl)cn([C@H](C)C3CC3)c2=O)c(C)n1

InChI Key InChIKey=NZIABYFTQSXPOJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313854   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50313854((R)-5-chloro-1-(1-cyclopropylethyl)-3-(6-methoxy-2...)
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed