BDBM50313859 (R)-5-chloro-1-(1-cyclopropylethyl)-3-(6-ethoxy-2,5-dimethylpyridin-3-ylamino)pyrazin-2(1H)-one::CHEMBL1077249

SMILES CCOc1nc(C)c(Nc2nc(Cl)cn([C@H](C)C3CC3)c2=O)cc1C

InChI Key InChIKey=SXWMDGBWAMZSGN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313859   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50313859((R)-5-chloro-1-(1-cyclopropylethyl)-3-(6-ethoxy-2,...)
Affinity DataIC50: 2.70nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed