BDBM50313866 (R)-5-chloro-1-(1-cyclopropylethyl)-3-(6-methoxy-5-methyl-2-(trifluoromethyl)pyridin-3-ylamino)pyrazin-2(1H)-one::CHEMBL1086179

SMILES COc1nc(c(Nc2nc(Cl)cn([C@H](C)C3CC3)c2=O)cc1C)C(F)(F)F

InChI Key InChIKey=KCAYYSLTKCCBHK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50313866   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50313866((R)-5-chloro-1-(1-cyclopropylethyl)-3-(6-methoxy-5...)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed