BDBM50314079 (5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-23-[(2S)-2-[(2S)-5-carbamimidamido-2-acetamidopentanamido]-3-phenylpropanamido]-8-[(4-hydroxyphenyl)methyl]-32-(1H-imidazol-4-ylmethyl)-4,22,22,25,26-pentamethyl-5-(2-methylpropyl)-3,6,9,10,16,24,27,30,33,36,42-undecaoxo-20,21-dithia-1,4,7,11,17,25,28,31,34,37-decaazatricyclo[36.3.1.0^{11,15}]dotetracontane-18-carboxamide::CHEMBL1089947
SMILES CC(C)C[C@@H]1N(C)C(=O)CN2CCC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@H](C)N(C)C(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]3CCCN3C(=O)C(=O)[C@H](Cc3ccc(O)cc3)NC1=O)C(N)=O)C2=O
InChI Key InChIKey=WGYWJJXNJFPTML-JHZPGZIOSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50314079
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals
Curated by ChEMBL
Syntonix Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals
Curated by ChEMBL
Syntonix Pharmaceuticals
Curated by ChEMBL
Affinity DataKd: 950nMpH: 7.4Assay Description:Binding affinity to soluble human FcRn at pH 7.4 by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals
Curated by ChEMBL
Syntonix Pharmaceuticals
Curated by ChEMBL
Affinity DataKd: 150nMpH: 6.0Assay Description:Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair