BDBM50314080 (3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-4-yl)methyl)-8-((S)-2-((S)-2-acetamido-5-guanidinopentanamido)-3-phenylpropanamido)-20-benzyl-32-(4-hydroxybenzyl)-11-((R)-1-hydroxyethyl)-29-isobutyl-7,7,25,28-tetramethyl-1,9,12,15,18,21,24,27,30,33,34-undecaoxohexatriacontahydropyrrolo[2,1-g][1,2,5,8,12,15,18,21,24,27,30,33]dithiadecaazacyclohexatriacontine-3-carboxamide::CHEMBL1089948

SMILES CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O

InChI Key InChIKey=XVQSPNCSNCKCMI-PCQLJHSASA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50314080   

TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314080((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-...)
Affinity DataIC50:  520nMAssay Description:Inhibition of IgG binding to soluble human FcRn after 5 hrs by competition ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314080((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-...)
Affinity DataKd:  170nMpH: 7.4Assay Description:Binding affinity to soluble human FcRn at pH 7.4 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIgG receptor FcRn large subunit p51(Homo sapiens (Human))
Syntonix Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50314080((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-...)
Affinity DataKd:  31nMpH: 6.0Assay Description:Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed