BDBM50314367 4-hydroxy-2-((4-(4-(4-(2-hydroxyethyl)piperazine-1-carbonyl)phenyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methylene)benzofuran-3(2H)-one::CHEMBL1092781

SMILES Cn1cc(\C=C2/Oc3cccc(O)c3C2=O)c2c(ccnc12)-c1ccc(cc1)C(=O)N1CCN(CCO)CC1

InChI Key InChIKey=ODKUJMMJYPRCMG-UQQQWYQISA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314367   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314367(4-hydroxy-2-((4-(4-(4-(2-hydroxyethyl)piperazine-1...)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50314367(4-hydroxy-2-((4-(4-(4-(2-hydroxyethyl)piperazine-1...)
Affinity DataIC50:  100nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed