BDBM50314370 3-(3-((4-hydroxy-3-oxobenzofuran-2(3H)-ylidene)methyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-N,N-dimethylbenzamide::CHEMBL1088746

SMILES CN(C)C(=O)c1cccc(c1)-c1ccnc2n(C)cc(\C=C3/Oc4cccc(O)c4C3=O)c12

InChI Key InChIKey=NIZRMSMNHMOGRS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50314370   

TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50314370(3-(3-((4-hydroxy-3-oxobenzofuran-2(3H)-ylidene)met...)
Affinity DataIC50: 18nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50314370(3-(3-((4-hydroxy-3-oxobenzofuran-2(3H)-ylidene)met...)
Affinity DataIC50: 369nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed