BDBM50314742 (R)-N-(2-{[(4-Ethoxyphenyl)carbonyl]amino}-3-hydroxypropyl)-1-phenyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide::CHEMBL1090544

SMILES CCOc1ccc(cc1)C(=O)N[C@@H](CO)CNC(=O)c1cn(nc1C(F)(F)F)-c1ccccc1

InChI Key InChIKey=AHZBLWURQMZRCN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50314742   

TargetDiacylglycerol O-acyltransferase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50314742((R)-N-(2-{[(4-Ethoxyphenyl)carbonyl]amino}-3-hydro...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DGAT1 expressed in baculovirus infected Sf9 cells using [14C]oleoyl-CoA after 15 mins by TLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed