BDBM50315043 CHEMBL1088810::N-(2-((3R)-1-(2-(4-benzoylpiperazin-1-yl)propyl)pyrrolidin-3-ylamino)-2-oxoethyl)-3-(trifluoromethyl)benzamide

SMILES CC(CN1CC[C@H](C1)NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)N1CCN(CC1)C(=O)c1ccccc1

InChI Key InChIKey=ZMXNGPQNWZCZQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315043   

TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315043(N-(2-((3R)-1-(2-(4-benzoylpiperazin-1-yl)propyl)py...)
Affinity DataIC50: 710nMAssay Description:Antagonist activity at human CCR2B receptor expressed in HEK293 cells assessed as inhibition of MCP1-induced increase in intracellular calcium levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Yangji Chemicals

Curated by ChEMBL
LigandPNGBDBM50315043(N-(2-((3R)-1-(2-(4-benzoylpiperazin-1-yl)propyl)py...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]MCP1 from human CCR2B receptor expressed in HEK293-EBNA cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed