BDBM50315209 1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1,3,5-triazin-2-yl)phenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)urea::CHEMBL1088970

SMILES CN1CCN(c2ccc(NC(=O)Nc3ccc(-c4nc(N5CC6CCC(C5)O6)nc(N5CC6CCC(C5)O6)n4)cc3)cc2)CC1

InChI Key InChIKey=BTQDPEATCSVQBM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315209   

TargetSerine/threonine-protein kinase mTOR(Rat)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315209BDBM50315209(1-(4-(4,6-di(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of rat brain mTOR assessed as p70S6K-GST protein phosphorylation after 30 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed