BDBM50315270 2-(4-tert-butylphenyl)-7-(4-((2-ethyl-5-methyl-1H-imidazol-4-yl)methyl)piperazin-1-yl)-3H-imidazo[4,5-c]pyridine::CHEMBL1092626

SMILES CCc1nc(C)c(CN2CCN(c3cncc4[nH]c(-c5ccc(C(C)(C)C)cc5)nc34)CC2)[nH]1

InChI Key InChIKey=YUZYLRYHIULMSV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315270   

TargetGonadotropin-releasing hormone receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315270BDBM50315270(2-(4-tert-butylphenyl)-7-(4-((2-ethyl-5-methyl-1H-...)
Affinity DataIC50: 58nMAssay Description:Displacement of [125I]D-Trp6-GnRH from human recombinant GNRH receptor by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315270BDBM50315270(2-(4-tert-butylphenyl)-7-(4-((2-ethyl-5-methyl-1H-...)
Affinity DataIC50: 290nMAssay Description:Displacement of [125I]D-Trp6-GnRH from rat recombinant GNRH receptor by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed