BDBM50315286 CHEMBL1088887::aR-6-(10-iodoethyl)-1,2,3,9,10,11-hexamethoxy-6-methyl-5H-dibenzo[a,c]cycloheptene

SMILES COc1cc2CC(C)(Cc3cc(OC)c(OC)c(OC)c3-c2c(OC)c1OC)C(C)I

InChI Key InChIKey=JAHZIXROXGDIMP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50315286   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Graz

Curated by ChEMBL
LigandPNGBDBM50315286(CHEMBL1088887 | aR-6-(10-iodoethyl)-1,2,3,9,10,11-...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of 5-LOX-mediated LTB4 production in stimulated human neutrophile granulocytes after 10 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed