BDBM50315404 (4'S)-3'-methyl-2-((4-oxo-2a,3,4,5-tetrahydropyrrolo[4,3,2-de]quinolin-1(2H)-yl)methyl)-6,8-dihydrospiro[cyclopenta[g]quinoline-7,4'-imidazolidine]-2',5'-dione::CHEMBL1090841
SMILES CN1C(=O)NC(=O)[C@@]11Cc2cc3ccc(CN4CC5CC(=O)Nc6cccc4c56)nc3cc2C1
InChI Key InChIKey=BKBXKZHHJMLDJU-KKFPZRRJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50315404
Affinity DataKi: 1.5nMAssay Description:Displacement of [125I]human CLR from human CGRP expressed in HEK293 cells coexpressing human RAMP1More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP production in t...More data for this Ligand-Target Pair
Affinity DataIC50: 7.30nMAssay Description:Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair