BDBM50315526 CHEMBL1090458::N-(4,5-dichlorothiophen-2-ylsulfonyl)-3-(3-methyl-1-(naphthalen-2-ylmethyl)-2-oxoindolin-7-yl)acrylamide

SMILES CC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cc(Cl)c(Cl)s1

InChI Key InChIKey=QYLYWIBUJSSCSR-VAWYXSNFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315526   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315526(CHEMBL1090458 | N-(4,5-dichlorothiophen-2-ylsulfon...)
Affinity DataIC50:  4.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315526(CHEMBL1090458 | N-(4,5-dichlorothiophen-2-ylsulfon...)
Affinity DataIC50:  3.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed