BDBM50315531 CHEMBL1093124::N-(3,4-dichlorophenylsulfonyl)-3-(1-(3,4-difluorobenzyl)-3-methyl-2-oxoindolin-7-yl)acrylamide

SMILES CC1C(=O)N(Cc2ccc(F)c(F)c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=PGBOUHOHRYNTKF-UXBLZVDNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315531   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315531(CHEMBL1093124 | N-(3,4-dichlorophenylsulfonyl)-3-(...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProstaglandin E2 receptor EP3 subtype(Human)
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50315531(CHEMBL1093124 | N-(3,4-dichlorophenylsulfonyl)-3-(...)
Affinity DataIC50:  95.8nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed