BDBM50315749 1-{4-[4-Morpholin-4-yl-7-(2-oxoethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]phenyl}-3-pyridin-4-ylurea::CHEMBL1091130

SMILES O=CCn1ccc2c(nc(nc12)-c1ccc(NC(=O)Nc2ccncc2)cc1)N1CCOCC1

InChI Key InChIKey=OGAYOZJQEPKLSG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315749   

LigandPNGBDBM50315749(1-{4-[4-Morpholin-4-yl-7-(2-oxoethyl)-7H-pyrrolo[2...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human PI3Kalpha by fluorescence polarization format assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315749(1-{4-[4-Morpholin-4-yl-7-(2-oxoethyl)-7H-pyrrolo[2...)
Affinity DataIC50: 3nMAssay Description:Inhibition of mTOR by DELFIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed