BDBM50316602 CHEMBL1099012::N-(5-Isothiocyanato-2-phenylindol-3-ylglyoxyl)-N'-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)-1,6-diaminohexane

SMILES O=C(NCCCCCCNc1ccc([N+](=O)[O-])c2nonc12)C(=O)c1c(-c2ccccc2)[nH]c2ccc(N=C=S)cc12

InChI Key InChIKey=RVVMGORJIPPDBD-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50316602   

TargetTranslocator protein(Rat)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316602BDBM50316602(N-(5-Isothiocyanato-2-phenylindol-3-ylglyoxyl)-N'-...)
Affinity DataKd:  8.31nMAssay Description:Irreversible binding affinity to TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316602BDBM50316602(N-(5-Isothiocyanato-2-phenylindol-3-ylglyoxyl)-N'-...)
Affinity DataKi:  37.6nMAssay Description:Displacement of [3H]Ro5-4864 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetTranslocator protein(Rat)
University of Pisa

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316602BDBM50316602(N-(5-Isothiocyanato-2-phenylindol-3-ylglyoxyl)-N'-...)
Affinity DataIC50: 42.2nMAssay Description:Displacement of [3H]Ro5-4864 from TSPO in rat kidney mitochondrial membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed