BDBM50316658 1-(2-ethoxyethyl)-3-methyl-5-(4-methylpiperazin-1-yl)-N-(4-methylpyridin-2-yl)-1H-pyrazolo[4,3-d]pyrimidin-7-amine::CHEMBL1094210

SMILES CCOCCn1nc(C)c2nc(nc(Nc3cc(C)ccn3)c12)N1CCN(C)CC1

InChI Key InChIKey=BQACRCDDFBIQAX-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50316658   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50316658(1-(2-ethoxyethyl)-3-methyl-5-(4-methylpiperazin-1-...)Copy SMILESCopy InChI

Affinity DataIC50: 2.60nMAssay Description:Inhibition of PDE5 in human platelet by assessed as hydrolysis of [3H]cGMP scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
12/30/2012
Entry Details Article
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