BDBM50316879 2-amino-8-(4-ethylpiperazine-1-carbonyl)-4-(4-fluorophenyl)-5H-indeno[1,2-d]pyrimidin-5-one::CHEMBL1087085

SMILES CCN1CCN(CC1)C(=O)c1ccc2C(=O)c3c(nc(N)nc3-c3ccc(F)cc3)-c2c1

InChI Key InChIKey=LOSSCOJTSWWTQO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316879   

TargetAdenosine receptor A2a(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316879(2-amino-8-(4-ethylpiperazine-1-carbonyl)-4-(4-fluo...)
Affinity DataKi:  32.1nMAssay Description:Antagonistic activity at adenosine A2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50316879(2-amino-8-(4-ethylpiperazine-1-carbonyl)-4-(4-fluo...)
Affinity DataKi:  191nMAssay Description:Antagonistic activity at adenosine A1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed